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diagnosis rheumatology differential treatment syndrome dermatology algorithm causes hepatology signs symptoms arthritis blood classification cppd cryoglobulinemia cryoglobulinemic gout hypertension mixed
Table 1. The ABC or (3Rs) of antidote mechanisms/actions. Br J Clin Pharmacol (2016) 81 402–407 #Management
The ABC or (3Rs) ... of antidote mechanisms ... /actions. ... 81 402–407 #Management ... #ABCs #Table
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rheumatologic, Vasculitides ... , IBD, Celiac disease ... syndrome, POEMS • Reaction ... Exercise, Allergic reactions
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... glomerulonephritis and/or pulmonary ... arthritis, obstructive pulmonary ... , drug reactions ... differential #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... deficiency • Liver disease ... Von Willebrand disease ... fever • Drug reactions ... Differential #Diagnosis #hematology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... IgA-associated vasculitis ... proteinuria, dysmorphic RBCs
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
failure - CAD/ACS ... - Tamponade Pulmonary ... HTN - Vasculitis ... Transverse myelitis • Hematology ... diagnosis #causes #pulmonary
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
due to lung disease ... pulmonary disease ... multifactorial mechanisms Hematologic ... neurofibromatosis, vasculitis ... , Gaucher disease
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
Nodosa (PAN) - Vasculitis ... Management Algorithm ... Guidelines • Severe Disease ... • Non-Severe Disease ... #Management #Treatment
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
AIHA, Transfusion reactions ... , Drugs, Liver Disease ... Electrolytes: Wilson's disease ... Smear ↑ abnormal RBCs ... Differential #Diagnosis #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
progressing GN • New pulmonary ... , drug reactions ... MPO > PR3) • Pulmonary ... Granulomas, IgE, pulmonary ... Differential #Diagnosis #Rheumatology
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