14 results
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Dermatomyositis (DM), Immune-Mediated ... Antisynthetase Syndrome ... Myopathy #Comparison #Managment ... #Rheumatology #Differential
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
DIAGNOSTIC CRITERIA ... primary or secondary immune ... chemotherapy) • Genetic syndromes ... Common variable immune ... diagnosis #hematology #Differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... Histopathologic criteria ... #Diagnosis #Management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... • Immune response ... intensive care unit (ICU ... Guillain #Barre #Syndrome ... #diagnosis #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Criteria for Diagnosis ... Resolution > 15 days Differentials ... Exanthematous Pustulosis Management ... SinaiBmoreIMRes #DRESS #Syndrome ... dermatology #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... life-threatening Differential ... : - Bedside: ice ... Gravis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... organ dysfuxtion, ICU ... Differentiation #Syndrome ... APML #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
cells are the immune ... diagnosis: months - Criteria ... : El Escorial criteria ... conditions listed in differential ... neurology #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... specific diagnostic criteria ... #Inflammatory #Syndrome ... #Differential # ... Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... mediated disease • Immune ... Diagnostic Criteria ... Myelitis #diagnosis #management ... #neurology #differential