9 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... • Calcineurin Inhibitors ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Common Diabetes Medications ... #Diabetes #Medications ... #pharmacology # ... pathophysiology ... #endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... - Pharmacology ... ketoacidosis (DKA ... #Pharmacology # ... DM2 #diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... different than other medications ... very tolerable medication ... Renal #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Type 2 Inpatient Medication ... Sulfonylurea, TZD, DPP-4 inhibitor ... α-glucosidase inhibitor ... #pharmacology # ... comparison #table #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... anti-diabetic medications ... #Pharmacology # ... Medications #DM2 ... #Diabetes #Endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
(EuDKA) SGLT2 Inhibitors ... Increasing Indications ... level < 200 mg/dL Pathophysiology ... diagnosis #management #endocrinology
Drugs for Depression and Anxiety Disorders

Selective Serotonin Reuptake Inhibitors
 • Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline,
Serotonin Reuptake Inhibitors ... Monoamine Oxidase Inhibitors ... to prevent NE, DA ... Anxiety #Disorders #Medications ... #Table #Pharmacology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Pathogenesis and Medications ... outflow - PDE-5 inhibitors ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology