6 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... usually IgG) (e.g. lupus ... (e.g. primary cold ... Extravascular #Causes #differential ... #anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Clinical Presentation ... presentation) • Cutaneous ... anemiaCold ... younger pts) Differential ... #anemia #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... , Cutaneous mimickers ... Other auto-immune, Infectious
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... fibromyalgia) • Infections ... lymphoproliferative syndrome Clinical ... lymphopenia, low PLT • Anemia
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
gangrenosum • Cutaneous ... • Coombs (-) hemolytic ... anemia due to cold ... IgG • Lupus anticoagulant ... #Monoclonal #Differential
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess - Clinical ... Leukocytosis, anemia ... > 10 days - Hemoptysis ... Coli - P.