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Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... with Pancytopenia ... • Toxins • Aplastic ... deficiencies #Pancytopenia ... Diagnosis #Algorithm #Causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... bone marrow + pancytopenia ... and petechiae Causes ... • Peripheral Pancytopenia
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Syndromes with Pancytopenia ... Anemia Acquired Aplastic ... lauraebrown #Pancytopenia ... BoneMarrow #Failure #Aplastic
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Autoimmune Mediated Pancytopenia ... FISH • Acquired Aplastic ... myelophthisis) #Pancytopenia
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... progresses to pancytopenia ... due to marrow aplasia ... more likely to cause
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Autoimmune Mediated Pancytopenia ... FISH • Acquired Aplastic ... myelophthisis) #Pancytopenia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Diagnosis: • Pancytopenia ... Medicine @SCVMCMed #Aplastic
Causes of Neutropenia - Differential Diagnosis Algorithm • Decreased Neutrophils Only • Bicytopenia / Pancytopenia #Neutropenia #Differential
Causes of Neutropenia ... Bicytopenia / Pancytopenia ... Diagnosis #Algorithm #Causes
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... progresses to pancytopenia ... due to marrow aplasia ... more likely to cause
Causes of Aplastic Anemia #Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Anemia #Aplastic ... #Anemia #Causes
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