28 results
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - Differential ... Donath-Landsteiner HA (paroxysmal ... hemoglobinuria) • Cold Agglutinin ... #Anemia #AIHA #Differential ... Diagnosis #Table #hematology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
( +/- ) Cold agglutinin ... , C3d ( +/- ) Paroxysmal ... #antiglobulin #test ... Autoimmune #Hemolysis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
younger pts) Differential ... macroglobulinemia Paroxysmal ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Differentiating Benign Paroxysmal Positional Vertigo (BPPV) From Vestibular Neuritis-Labyrinthitis
BENIGN PAROXYSMAL POSITIONAL VERTIGO
 • Age: More common
Differentiating Benign Paroxysmal ... Neuritis-Labyrinthitis BENIGN PAROXYSMAL ... ) • Hallpike test ... ) • Epley maneuver ... saccade seen) • Epley
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Transfusion reaction, Paroxysmal ... . primary cold agglutin ... Extravascular #Causes #differential ... #diagnosis #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... erythematosus • HLH • Paroxysmal ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
abnormal liver tests ... obgyn #obstetrics #hepatology ... #diagnosis #differential
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... incompatibility • Paroxysmal ... Hemolytic #Anemia #Differential ... classification #hematology
Benign Adrenal Mass - Differential Diagnosis Algorithm
Hyperplasia - Often Bilateral
 • Congenital Adrenal Hyperplasia
 • ACTH
Adrenal Mass - Differential ... Dexamethasone Suppression Test ... Pheochromocytoma (Paroxysmal ... AdrenalMass #Benign #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Agglutination - Cold agglutinins ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology