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diagnosis hematology workup algorithm hemolysis agglutinin cold disease disorders extravascular hodgkins intravascular lymphoma management mcv oncology platelet thrombocytopenia thromboticthrombocytopenicpurpura ttp
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Hematology #Diagnosis ... GrepMed Recommended Text
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... erythematosus • HLH • Paroxysmal ... Antibody-mediated hemolysis ... Diagnosis #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... incompatibility • Paroxysmal ... #Anemia #Differential ... #classification ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... Transfusion reaction, Paroxysmal ... #differential # ... #anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... • Bleeding • Hemolysis ... #MCV #Classification ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... K), H. pylori test ... changes), high MCV anemia ... ITP, unexplained pancytopenia ... #Workup #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
younger pts) Differential ... macroglobulinemia Paroxysmal ... • Diagnostic Test ... Donath-Landsteiner test ... #anemia #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
value is low, tests ... result in severe anemia ... indirect antiglobulin tests ... anemia Indirect ... WBC count and differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... ) Classification ... Immunohistochemical studies (to differentiate
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