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diagnosis management rheumatology dermatology differential systemic generalized latenttb pruritus signs symptoms tb treatment tuberculosis abnormal agglutinin alopecia amyloid amyloidosis anemia
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and clinical associations ... trigger - Direct skin ... - Ice cube test ... Urticaria #diagnosis #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Liver Function Tests ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #causes
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
• Autoantibody activity ... cryoglobulinemia, Cold ... agglutinin disease ... manifestations #dermatology ... #skin #clinical
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Nail Fold Abnormality ... • Nephrotic syndrome ... #Diagnosis #Algorithm ... #causes
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Syndrome (CAS): ... Viral Infection Clinical ... • Diagnostic Test ... #anemia #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... matter, spinal cord ... (Clinical Dx). ... (this is a skin ... signs #symptoms #rheumatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
algorithm. ... urgent referral to secondary ... presence of metabolic syndrome ... or referral to secondary ... #Hepatology #Liver
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Liver Function Tests ... Myelodisplastic syndrome ... #Pruritus #secondary ... #causes
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
miliary TB Secondary ... extrapulmonary Secondary ... characteristic features Clinical ... • Tuberculin skin ... test (TST) • Interferon-γ
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