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management hematology lupus differential erythematosus syndrome systemic workup activation ana antinuclear autoantibodies behcet chronic cll comparison druginduced genetics iem inbornerrors
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
complex storage diseases ... See the lab values ... Pathophysiology #Diagnosis ... #Algorithm #Differential ... #Table #IEM #NICU
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... • Specific for SLE ... Treatment: • ... #Summary #diagnosis ... #rheumatology #
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... clinically suspected, tests ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
is a skin prick test ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
life-threatening • Treatment ... Evolution: Chronic disease ... #comparison #table ... #rheumatology # ... diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... Liver function tests ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... some time, let’s see ... As with many disease ... Best to have an ... #Algorithm #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... adults in the west ... phenomenon CLL Diagnosis ... cells can indicate disease ... microglobulin Treatment
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cases such as: • SLE ... : • Clinical tests ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management
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