10 results
Brittle nails and hair loss in hypothyroidism- ...Physical examination revealed dry skin, thickened and brittle nails
examination revealed dry skin ... thyroiditis was diagnosed ... the differential diagnosis ... #clinical #photo ... #NEJM #hypothyroidism
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
base, with loss ... with increased blood ... #Diseases #Abnormal ... #Pathology #Diagnosis ... #Clinical #Signs
Disseminated Cutaneous Blastomycosis- A fungal culture of skin tissue was negative; however, a skin biopsy showed
fungal culture of skin ... negative; however, a skin ... staining confirmed a diagnosis ... #clinical #photo ... #derm #NEJM #cutaneous
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
wax and wane; diagnosis ... trauma leads to skin ... leishmania, Tb, NTM; less ... Sporotrichiosis #Infection #clinical ... #photo #hand
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Anorexia • Weight loss ... pulses, bruits, or blood ... malaise, weight loss ... fluid (CSF) is abnormal
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Amyloidosis Clinical ... macroglossia Nails ... unintentional weight loss ... Testing Blood
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... arthritis, weight loss ... 3rd Decade Skin ... Differential Diagnosis ... Seizures • Strokes Skin
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Syndromes (specific loss-of-function ... Aplastic Anemia Clinical ... Headaches • Pale skin ... result from low blood ... oncology #hematology #diagnosis
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... steroid use Dx: skin ... hyphae invading blood ... #dermatology #skin ... #clinical #photo
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
• Major blood ... has five major clinical ... fungal stain of clinical ... vagina, fingers, nails ... have positive blood