14 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... Infectious manifestations ... #differential # ... #dermatology #oncology ... #clinical #skin
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
Sporotrichiosis Infection ... trauma leads to skin ... systemic signs, labs normal ... biopsy preferred Differential ... #clinical #photo
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... petechiae) • Frequent infections ... • Parvovirus infection ... count with differential ... diagnosis #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... Idiopathic • Infections ... result from low blood ... Aplastic #Anemia #oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... cell arteritis Infections ... vasculitis (inflamed blood
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cooled from the normal ... which can plug blood ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Antiphospholipid syndrome
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... to exclude are infections ... pulses, bruits, or blood ... fluid (CSF) is abnormal
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... diagnosis #workup #oncology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... neurological lesion: Clinical ... Infections: - ... Blockage of the Blood ... MCTD, Sjogren syndrome
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... • Polymorphic skin ... , • Multiple skin ... Chest pain, cough, bloody