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diagnosis treatment differential neurology symptoms arteritis behcet causes cerebritis coagulation dic disease disseminated fungal gca giantcell hematology infections infectiousdiseases intravascular
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Systemic Lupus Erythematosus ... Disease, PRES Pathophysiology ... #rheumatology # ... cerebritis #diagnosis #management
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Diagnosis and Management ... Unilateral • Signs ... lesions (a), Brain: normal ... #treatment #rheumatology ... #ophthalmology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... inhibitors • Uveitis- Ophthalmology ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... - APTT < 1.5 x normal ... causes #treatment #management ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... them, but urgent rheumatology ... required +/- prompt ophthalmology ... GCA #Temporal #Signs ... Symptoms #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... ischemia • Skin: Erythematous ... fluid (CSF) is abnormal ... chorioretinitis, CNS ... Differential #Diagnosis #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... • Bilateral signs ... Sjogren's • CSF: - Abnormal ... Myelitis #diagnosis #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
systemic lupus erythematosus ... cell lymphoma Pathophysiology ... phosphatase - Normal ... TAFRO #diagnosis #management ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... Fungal #Diagnosis #Management
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