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diagnosis treatment algorithm arteritis giantcell signs symptoms 2ndline aion anteriorischemicopticneuropathy apml causes centralretinalartery coagulation crisis dic differential differentiation disseminated giantcellarteritis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
GCA, SLE, GPA) - ... congenital defects) -> Abnormal ... anti-coagulation • Hematologic ... #pathophysiology ... #ophthalmology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
cell arteritis (GCA ... Typical symptoms of GCA ... Abnormal TAB ... #Rheumatology # ... Ophthalmology #Diagnosis
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
cell arteritis (GCA ... mg/kg/day (AION/CRAO ... giantcell #arteritis #GCA ... #Treatment #Management ... #Indications #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Idiopathic • Normal ... ANCA (C-ANCA): GPA ... eGPA, MPA >>> GPA ... diagnosis #algorithm #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
cell arteritis (GCA ... , but normal values ... them, but urgent rheumatology ... required +/- prompt ophthalmology ... Symptoms #Diagnosis #Management
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Diagnosis and Management ... lesions (a), Brain: normal ... Neuritis #Diagnosis #Management ... #treatment #rheumatology ... #ophthalmology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... causes #treatment #management ... #hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
hypertension 3) Abnormal ... anemia (MAHA) Pathophysiology ... of arteries Management ... Renal #Crisis #rheumatology ... nephrology #diagnosis #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
cell lymphoma Pathophysiology ... phosphatase - Normal ... TAFRO #diagnosis #management ... #rheumatology #
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