18 results
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Xerophthalmia - abnormal ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Diagnosis and Management ... Unilateral • Signs ... lesions (a), Brain: normal ... #treatment #rheumatology ... #ophthalmology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
should reveal normal ... acuity If any are abnormal ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Doppler US : halo sign ... efficacy of GCs Abnormal ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... JAK2 mutation OR Abnormally ... present, symptoms, signs ... PV #Diagnosis #Management ... Summary #treatment #hematology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
congenital defects) -> Abnormal ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... them, but urgent rheumatology ... required +/- prompt ophthalmology ... GCA #Temporal #Signs ... Symptoms #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... causes #treatment #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology