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diagnosis nephrology differential algorithm treatment causes potassium low barre guillain rhabdomyolysis alkalosis bartter brash chloride gbs guillainbarre hyponatremia hypotonic metabolic
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome • Urine Chloride • Urine Ca/Cr ratio Dr. Krithika
Differentiating Gitelman ... syndrome • Urine ... Chloride • Urine ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... • Cell shift: Hypokalemic ... , Gitelman syndrome ... #hypokalemia ... algorithm #diagnosis #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... Metabolic alkalosis • Normal ... Hypocalciuria (spot urine ... #nephrology #management ... #pathophysiology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... H+ secretion → Hypokalemia ... #Syndrome #Pathophysiology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Extra-renal Losses: • Normal ... , Gitelman syndrom ... @priti899 #Hypokalemia ... potassium #low #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... • Diarrhea A urine ... consumption • Low/Normal ... , Gitelman syndrome ... differential #potassium #nephrology
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... Al, Normal R - ... , Gitelman's syndrome ... #Hypokalemia # ... Diagnosis #Algorithm #nephrology
Gitelman Syndrome - Management Treatment includes - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... In persistent hypokalemia ... #Syndrome #Management ... #Treatment #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Normal ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... In a normal gap ... #Algorithm #nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... Elevated Renin Urine ... Renal Imaging: - Normal ... #Workup #nephrology
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