6 results
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... ABG And BMP Normal ... D-lactate (short bowel syndrome ... Volume depletion (diuresis ... Classically” noted with pulmonary
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... irrigation • Management ... Bumetanide, Ethacrynic acid ... Torsemide) • Acute pulmonary ... #Nephrology #Pharmacology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... • Triggers: Diuretics ... febrile, give abx ... Elevated uric acid ... TLS #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... Supportive Care: Diuresis ... APML #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... : • Anti-GAD Ab ... SPS #Diagnosis #Management ... #treatment #neurology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... Metabolic alkalosis • Normal ... Surreptitious diuretic ... #diagnosis #nephrology ... #management #pathophysiology