10 results
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... ABG And BMP Normal ... D-lactate (short bowel syndrome ... Classically” noted with pulmonary ... #ABG #bloodgas
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... febrile, give abx ... : • Pathophysiology ... Elevated uric acid ... TLS #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... : • Anti-GAD Ab ... Treatment: • ... #treatment #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... CSF PROTEIN - NORMAL ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... APML #diagnosis #management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Bumetanide, Ethacrynic acid ... Torsemide) • Acute pulmonary ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... and cauda equina TREATMENT ... #diagnosis #management ... #neurology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
by culture or serology ... level • A low or normal ... Aspergillosis Pathophysiology ... Diagnosis: • Serology ... Fungal #Diagnosis #Management
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... Metabolic alkalosis • Normal ... Rhabdomyolysis Treatment ... #diagnosis #nephrology ... #management #pathophysiology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
disorders, including acid ... cell lymphoma Pathophysiology ... phosphatase - Normal ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management