11 results
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Primary HLH: - ... transplantation Secondary ... HLH: • Approach ... #Treatment #management ... #hematology
Nail Disorders - Primary and Systemic Causes - Differential Diagnosis Algorithm

#NailDisorders #Primary #Secondary #Systemic #dermatology #Differential
Nail Disorders - Primary ... and Systemic Causes ... #Secondary #Systemic ... #dermatology #Differential ... #causes
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... A subset of hemophagocytic ... lymphohistiocytosis (HLH ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... assessment+++ Primary ... #Hemophagocytic ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... Primary Causes ... #secondary #systemic ... #generalized #dermatology ... #causes
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... Primary (Familial ... Treatment Approach ... #HLH #Hemophagocytic ... #Hematology #HemeOnc
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Approach to Elevated ... into a 4-pass system ... pass = Dangerous secondary ... Chronic & Rx-related Secondary ... 3rd pass = Primary
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... frequently affected systems ... Better call hematology ... up EPO levels Primary ... causes: Many of
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential ... #causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... other diseases • Secondary ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... #Diagnosis #Management