30 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal Coagulation ... PT - Prolonged aPTT ... #Algorithm #Coagulation ... #Abnormal #APTT ... Hematology #Diagnosis #Workup
Coagulation Protein Tests (PT and PTT)

#Coagulation #Tests #PTT #algorithm #differential #pathophysiology
Coagulation Protein ... Tests (PT and PTT ... ) #Coagulation ... #Tests #PTT #algorithm
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... Congenital intrinsic coagulation ... intravascular coagulation ... differential #hematology #coagulation
Coagulation Cascade Mnemonic - PITT vs PET
PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... = Intrinsic = APTT ... @pinoygastro #Coagulation
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... @DharSaty #coagulation ... vWF #thrombin #ptt
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... • Prolonged PT/PTT ... is simultaneous coagulation ... PT/INR: ↑ • PTT ... INR < 2.3 - APTT
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
INR), Prolonged PTT ... INR), Prolonged PTT ... (INR), Normal PTT ... • Prolonged PTT ... Causes #Hematology #coagulation
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Anticoagulants on Coagulation ... Tests PT / INR, aPTT
Chest Pain - Diagnosis and Workup Algorithm

History and Exam
Acute life-threatening causes:
 • Acute myocardial infarction
 •
Diagnosis and Workup ... rupture Initial workup ... LET, lipase, PT. aPTT ... Diagnosis #Algorithm #workup
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
/uL Initial Workup ... iron studies, PT/aPTT ... Algorithm #hematology #workup