13 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... seizure, primitive reflexes ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #signs #symptoms
Clinical features of focal cortical brain lesions in a right-handed individual

Frontal, either:  
Intellectual impairment, 
Personality
right: Dressing apraxia ... left: Limb apraxia ... #Localization #Symptoms ... #Signs #Diagnosis ... #Neurology
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
Algorithm Cerebral ... • Apraxia • ... Cognition/Confusion, Dementia ... Brown-Sequard Syndrome ... #Hemiplegia #Neurology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute B1 ... dysfunction (e.g. gait ataxia ... treatment can improve symptoms ... development of Korsakoff syndrome ... #Management #neurology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
slowness, Psychosis/dementia ... , Ataxia, Poverty ... Carpal timel syndrome ... Slow-relaxing reflexes ... #Symptoms #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... bladder and rectal reflex ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
- Differential Diagnosis ... Algorithm Red ... papilledema • Horner syndrome ... ) • Systemic symptoms ... #Algorithm #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Cramping, Weakness, Ataxia ... Signs and symptoms ... objective evidence of neurologic ... #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes ... #neurology #differential ... #algorithm
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Lower motor neuron symptoms ... in deep tendon reflexes ... #differential #diagnosis ... #neurology