16 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... seizure, primitive reflexes ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #signs #symptoms
Clinical features of focal cortical brain lesions in a right-handed individual

Frontal, either:  
Intellectual impairment, 
Personality
right: Dressing apraxia ... left: Limb apraxia ... #Localization #Symptoms ... #Signs #Diagnosis ... #Neurology
Guillain-Barre Syndrome
An acute polyneuropathy (disorder Of the peripheral nervous System).
Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... Symptoms are Often ... GuillainBarre #Syndrome ... #Diagnosis #Neurology ... #Signs
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
Algorithm Cerebral ... • Apraxia • ... Cognition/Confusion, Dementia ... Brown-Sequard Syndrome ... #Hemiplegia #Neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
, Mild sensory symptoms ... or signs, Cranial ... nervous system signs ... #Syndrome #diagnosis ... #criteria #neurology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
slowness, Psychosis/dementia ... , Ataxia, Poverty ... Carpal timel syndrome ... Slow-relaxing reflexes ... #Symptoms #Diagnosis
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Decreased / Absent Reflexes ... Diagnosis: • ... #Syndrome #diagnosis ... management #treatment #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... bladder and rectal reflex ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Differential Diagnosis ... cord • Guillain-Barre ... #causes #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
- Differential Diagnosis ... Algorithm Red ... papilledema • Horner syndrome ... ) • Systemic symptoms ... #Algorithm #neurology