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diagnosis amiodarone apml associated differential differentiation disorder hand hematology immune inflammatory iris lung neurocognitive neurology oncology pulmonary reconstitution toxicity toxicology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... The clinical syndrome ... inattention and reduced ... #AIDS #Neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... endothelial damage • Induce ... Diagnosis: >3 symptoms ... APML #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... /AIDS patients ... be present: • AIDS ... skin lesions, ocular ... Differential #Diagnosis #Management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
respiratory distress syndrome ... gradually with symptoms ... • Reticular + Nodular ... Improvement in symptoms ... Pulmonary #diagnosis #management
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