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diagnosis differential management rheumatology associated erythematosus hand hiv inflammatory iris lupus manifestations neurocognitive neuromyelitis optica reconstitution signs sle systemic transverse
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... • Transverse myelitis ... pain • Extra-CNS ... Comorbid autoimmune disorders ... #symptoms #signs
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... pulmonary etc) • CNS ... -> PNS -> NMJ - ... • Inflammatory disorders ... Polymyositis • Immune
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
and infects the CNS ... mononuclear cells in the CNS ... • Depressive symptoms ... #dementia #AIDS ... #Neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... mediated disease • Immune ... Bilateral signs and/or symptoms ... diagnosis #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... polyangiitis • No ... chorioretinitis, CNS
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... context of primary immune ... and CNS • Headache ... • Transverse Myelitis ... Induced Lupus: • Symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... pleural effusions, CNS ... skin lesions, ocular
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