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diagnosis differential management rheumatology associated behcet disease hand hiv inflammatory iris manifestations myelitis neurocognitive neuromyelitis optica reconstitution transverse vasculitis weakness
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... pain • Extra-CNS ... Comorbid autoimmune disorders ... Manifestations #diagnosis #neurology ... #symptoms #signs
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
and infects the CNS ... mononuclear cells in the CNS ... • Depressive symptoms ... #dementia #AIDS ... #Neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... pulmonary etc) • CNS ... -> PNS -> NMJ - ... Lack of UMN/LMN signs ... Polymyositis • Immune
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... collaboration • CNS ... diagnosis #management #signs
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... • Bilateral signs ... and/or symptoms ... diagnosis #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... polyangiitis • No ... chorioretinitis, CNS
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... pleural effusions, CNS ... skin lesions, ocular
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