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diagnosis differential management rheumatology hiv inflammatory signs associated bee behcet cns disease erythematosus infections infectiousdiseases iris lupus manifestations myelitis neurocognitive
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Immune-mediated ... conjunction with symptoms ... nervous system (CNS ... optica spectrum disorder ... #neurology #inflammatory
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... pain • Extra-CNS ... Comorbid autoimmune disorders ... Manifestations #diagnosis #neurology ... #symptoms #signs
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
impairment • HIV dementia ... • Depressive symptoms ... The clinical syndrome ... #dementia #AIDS ... #Neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... required until immune ... Suspect in movement disorders ... focal neurologic ... differential #diagnosis #AIDS
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... pulmonary etc) • CNS ... • Inflammatory disorders ... Polymyositis • Immune ... Differential #Diagnosis #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... skin injury) • Neurologic ... symptoms (headache ... aneurysms Diagnosis: No ... management #signs #symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic ... polyangiitis • No
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... mediated disease • Immune ... /or symptoms • ... diagnosis #management #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... skin lesions, ocular ... Zoster flare, ocular
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... context of primary immune ... CNS • Headache ... mood disorder ... Induced Lupus: • Symptoms
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