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diagnosis differential management rheumatology inflammatory signs associated bee behcet disease erythematosus hand hiv iris lupus manifestations myelitis neurocognitive neuromyelitis optica
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Immune-mediated ... nervous system (CNS ... optica spectrum disorder ... ANCA-associated vasculitides ... #neurology #inflammatory
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... pain • Extra-CNS ... Comorbid autoimmune disorders ... Manifestations #diagnosis #neurology ... #symptoms #signs
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... pulmonary etc) • CNS ... • Inflammatory disorders ... Polymyositis • Immune ... Differential #Diagnosis #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic ... polyangiitis • No
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... skin injury) • Neurologic ... symptoms (headache ... aneurysms Diagnosis: No ... management #signs #symptoms
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
impairment • HIV dementia ... • Depressive symptoms ... The clinical syndrome ... #dementia #AIDS ... #Neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... Bilateral signs and/or symptoms ... - Sjogren - Vasculitis ... diagnosis #management #neurology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... ) • Endocrine disorders ... context of primary immune ... involve PNS and CNS ... Induced Lupus: • Symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... skin lesions, ocular ... Zoster flare, ocular
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