15 results
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Diagnosis Type ... delivery: Hypoxemia, Anemia ... Type B Lactic Acidosis ... Diagnosis #TypeA ... #TypeB #lactate
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Anemia 1) DIAGNOSE ... Coombs • IgG type ... • Blood smear: Differential ... #Anemia #diagnosis ... management #treatment #rheumatology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - ... Differential Diagnosis ... Disease Mixed-type ... Differential #Diagnosis ... #Table #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis ... Diagnosis #Hematology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Graves' Disease Type ... Serum sickness Type ... Allergic #Reactions #Types
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... younger pts) Differential ... #anemia #hematology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
workup What type ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... MNCD #Dementia #Differential ... #Subtypes #Classification
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Type A: Impaired ... Shock, Severe Anemia ... , Cardiac Arrest ... dysfunction Type ... Thiamine & Biotin) Type
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
protein receptor type ... activin A receptor type ... Schistosomiasis - Chronic hemolytic ... anemia - Persistent ... #Diagnosis #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
are listed as Type ... Nonhypoxic • Type ... - Alcohol • Type ... - Propofol • Type ... #typea #typeb #