30 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... • Arthralgia ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Deposition - Arthralgia ... Myopathy (Also caused ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Measles (Rubeola) 
Clinical 
 • High fever 
 • Cough, Coryza, Conjunctivitis (The 3 C's)
Clinical • High fever ... Koplik spots Complications ... Pneumonia (most common cause ... rnortality) • Acute ... Features #Symptoms #Signs
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... becomes more severe Signs ... • High grade fever ... #pathophysiology ... #symptoms #signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Clinical Findings Risk ... chromosome 21) Signs ... / Symptoms / Complications ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... High-risk Features ... Ill-appearing, vital sign ... instability - New-onset fever ... Color #Targetoid #Algorithm
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
hypotension develops • Risk ... vomiting • Fatigue Signs ... • Low-grade fever ... Back pain • Arthralgia ... Reduced libido • Signs
Diseases of the Biliary Tract
Asymptomatic gallstones - Asymptomatic
Symptomatic gallstones - Biliary pain
Cholesterolosis of gallbladder - Usually
asymptomatic, high risk ... gallbladder cancer Acute ... , vomiting, fever ... , Murphy sign Chronic ... pain, jaundice, fever
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
pneumonia • Acute ... infections • Acute ... Non-Infectious Causes ... : Temperature rises ... Brucellosis Faget's Sign
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
vasoconstrictive • Acute ... narrowing and vascular ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms #complications