6 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... protein C and S Pathophysiology ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... #management #hematology
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
adjusted d-dimer ... 88 = age adjusted ... #dimer #pathophysiology ... #hematology #differential ... #diagnosis #age
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... Disseminated intravascular ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and the aPTT ... hemorrhage • Disseminated ... #Causes #diagnosis ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Diagnosis Framework ... liver failure, disseminated ... intravascular coagulation ... discern these causes ... #Diagnosis #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
be performed PT ... products or D-dimer ... reflection of intravascular ... WBC count and differential ... #Workup #Hematology