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diagnosis treatment hemophagocytic hlh lymphohistiocytosis rheumatology antifungals causes coagulation coccidioides coccidioidomycosis cop cryptogenic dic disseminated hemeonc ild intravascular organizing pharmacology
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
pneumonia • formerly BOOP ... • Type of interstitial ... Organizing Pneumonia - Clinical ... sputum culture, urinary ... ILD #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop ... accumulation of clinical ... Assessment • Clinical ... assessment+++ Primary ... Lymphohistiocytosis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... or venipuncture sites ... Treatment: • Treat primary ... causes #treatment #management ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
IV RTA, TYPE I ... salivary ducts Clinical ... nephritis • Distal (Type ... Nephrogenic DI Hematologic ... #Diagnosis #Management
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis. Fluconazole - Low
Penetrates most body sites ... Efficacious against primary ... tolerable • Limited clinical ... #valleyfever #management ... #antifungals #comparison
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Types of HLH • ... Primary (Familial ... Clinical Presentation ... #Hematology #HemeOnc
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