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diagnosis hematology apml atlas comparison differentiation disease framework hellp hepatitis hepatology key liver morphology nonpalpable obstetrics oncology palpable pregnancy purpura
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
of Pregnancy (ICP ... necrosis HELLP Syndrome ... DIC • Aminotransferases ... hepatitis #comparison #differential ... #HELLP #AFLP
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
uremic syndrome ... thrombocytopenia (ITP ... coagulopathy (DIC ... key #diagnosis #differential ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... - Bacterial: Sepsis ... Microangiopathy: DIC ... Antibody-mediated: ITP ... antiphospholipid syndrome
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Thrombocytopenia: ITP ... /TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
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