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diagnosis hematology hemolysis rheumatology activation agglutinin atlas causes classification cold common cvid disease extravascular hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular key
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... transplant • DIC ... anemia" • HELLP ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... intravascular coagulation (DIC ... uremic syndrome ... Extravascular #Causes #differential ... #anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... uremic syndrome ... coagulopathy (DIC ... key #diagnosis #differential ... #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... MAHA: TTP, HUS, DIC ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /TTP/HUS - Hemolytic ... anemia - Splenomegaly ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... anemia • Cold ... younger pts) Differential ... #anemia #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and autoimmune hemolytic ... anemia) • Systemic ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... brucellosis) • Sepsis ... with leukopenia, anemia ... #Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... anemia • Pain ... Immunohistochemical studies (to differentiate ... #oncology #management
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