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diagnosis hematology management causes classification acidosis activation algorithm anesthesia anesthesiology aplastic apml cell checklist chronic cll differentiation elevation hodgkins hyperthermia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... Constitutional Syndromes ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... #oncology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... anaesthesia • Sepsis ... #Hyperthermia #Differential ... Diagnosis #Management #Workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Neutropenia, anemia ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... brucellosis) • Sepsis ... with leukopenia, anemia ... Treatment: • Corticosteroids
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #oncology #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome ... 30mmHg) - Severe anemia
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... • No CRAB - no anemia ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
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