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diagnosis oncology algorithm lymphadenopathy diffuse focal localized anemia cardiology classification extravascular hemolysis hemolytic hodgkins intravascular leukemia lymphoma management mds myelodysplasia
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Neoplastic (Leukemia, Lymphoma ... Lymphadenopathy #LAD ... #Differential # ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Young age ... Asymptomatic, Age ... Lymphadenopathy #LAD ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Epitrochlear (Always pathologic ... Lymphadenopathy #LAD ... #Differential # ... #Hematology #Oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... e.g. lupus, CLL, lymphoma ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... has a bimodal age ... (90-95% of cases ... Immunohistochemical studies (to differentiate ... classification #hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... : • Advanced age-arteriosclerosis ... Well-conditioned athletes Pathologic ... Vasoplegia • Sepsis ... systolic hypertension had
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... Small lymphocytic lymphoma ... of large cell lymphoma ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Mean age at Dx ... 70-75 years of age ... compounds, alcohol, lead ... blood count with differential ... Syndromes #diagnosis #hematology
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