9 results
An Approach to Jaundice - Differential Diagnosis

- Increased Production (Prehepatic)
- Decreased Clearance (Intrahepatic + Posthepatic)

Dr. Eric
to Jaundice - Differential ... #Jaundice #Differential ... #Table #Causes ... Posthepatic #Diagnosis #Hepatology ... #bilirubinemia
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Elevated Transaminases ... / Transaminitis ... - Differential ... #Elevated #Transaminases ... Diagnosis #causes #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Algorithm for Transaminitis ... Drugs, Infection, Sepsis ... kwburak #LFTs #Elevated ... Algorithm #diagnosis #hepatology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Hepatic Uptake • Sepsis ... #Jaundice #Differential ... Algorithm #Causes #Hepatology ... #bilirubinemia
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - Differential ... #Tests #LFTs #Differential ... #Diagnosis #hepatology ... #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Drugs • TPN • Sepsis ... Others #LFTs #Hepatology ... #LiverEnzymes #Differential
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm

 • Chronic Myocardial Injury: End
Myocardial Injury - Elevated ... Troponin Differential ... Occlusion • Stable ... Myocardial #Injury #Elevated ... #Troponin #Differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if WBC > 5 or elevated ... initiation • Differential ... Diagnosis: Infection (sepsis ... diagnosis #management #hematology