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diagnosis hematology coagulation aptt prolonged acronym aflp anemia bleeding bruising cirrhosis cryofibrinogenemia disseminated hellp hemostasis hepatitis icp intravascular liver management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
history of trauma, sepsis ... • Prolonged PT ... Fibrinogen: ↓ • PT ... • Severe Liver Disease ... Treat primary cause
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... intravascularcoagulation (DIC ... amyloidosis #Abnormal ... #differential # ... hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... intravascular coagulation (DIC ... #differential # ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... Acquired: • Heparin ... PT/NORMAL PTT: ... ABNORMAL PT/
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... DIC • Aminotransferases ... #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic for Causes ... Platelet Disorders (DIC ... Spleen L - Liver Disease ... Toxin (Drug or Heparin-induced ... Thrombocytopenia #Differential
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... , Inflammation NORMAL ... gastric, rectal, Peptic ... , DIC-low factor ... #Diagnosis #Hepatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cooled from the normal ... cryoglobulins • Negative causes ... skin necrosis • DIC ... • Septic emboli ... #rheumatology #hematology
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