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diagnosis hematology coagulation aptt obstetrics prolonged thrombocytopenia acronym aflp algorithm bleeding bruising disease disseminated framework hemorrhage hemostasis hepatitis intravascular liver
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
of Pregnancy (ICP ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... - Bacterial: Sepsis ... Microangiopathy: DIC ... - Pregnancy: HELLP
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
history of trauma, sepsis ... • Prolonged PT ... Fibrinogen: ↓ • PT ... Treat primary cause ... Coagulation #diagnosis #causes
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... intravascularcoagulation (DIC ... amyloidosis #Abnormal ... #differential # ... hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... intravascular coagulation (DIC ... Jcortesizaguirr #Abnormal ... #differential # ... hematology #coagulation
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... succenturiate lobe • Abnormal ... purpura (TTP) • HELLP ... intravascular coagulation (DIC ... Anti-coagulation agents (e.g. heparin
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... Acquired: • Heparin ... PT/NORMAL PTT: ... ABNORMAL PT/
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic for Causes ... Platelet Disorders (DIC ... , ITP, TTP) L - ... Toxin (Drug or Heparin-induced ... Thrombocytopenia #Differential
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