9 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... syndrome (HUS) ... #Hemolytic #Intravascular ... #Causes #differential
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... TTP/HUS indicates ... purpura/hemolytic ... , Hematology 2012 ... #Diagnosis #Differential
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... #purpura #TTP # ... #thrombocytopenia ... Comparison #Diagnosis #Table ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis Table ... • Thrombotic Thrombocytopenic ... Purpura (TTP) ... Microangiopathy #TMA #hematology ... #differential #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... disease - DIC/TTP/HUS ... - Hemolytic ... : • DIC, TTP/HUS ... #Differential #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... history of trauma, sepsis ... Petechiae • Purpura ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... reflection of intravascular ... WBC count and differential ... Diagnosis #Workup #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Post Transfusion Purpura ... Causes purpura & ... severe thrombocytopenia ... Occurs between 0-6 hrs ... Can lead to sepsis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Post Transfusion Purpura ... Causes purpura & ... severe thrombocytopenia ... Occurs between 0-6 hrs ... Can lead to sepsis