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diagnosis hematology blood causes product reactions algorithm anemia bilirubinemia classification extravascular hodgkins intravascular jaundice lymphoma oncology schistocytes transfusion transfusions
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
fragmentation hemolysis ... toxin-mediated hemolytic-uremic ... • Mechanical hemolysis ... macroangiopathic hemolytic ... #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... hemolytic anemia ... purpura (TTP), Hemolytic ... uremic syndrome (HUS
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Production • Hemolysis ... Hepatic Uptake • Sepsis ... Post-Hepatic - Usually has ... Algorithm #Causes #Hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... • Acute Hemolytic ... Hemolysis on labs ... etc) • Delayed Hemolytic ... , fever, minor hemolysis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Febrile Non-Hemolytic ... - Acute Hemolytic ... Hemolysis on labs ... - Delayed Hemolytic ... , fever, minor hemolysis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
persons • It has ... nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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