11 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... Thrombocytopenic Purpura ... Microangiopathy #TMA #hematology ... #differential #
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombocytopenic purpura ... /hemolytic uremic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... thrombocytopenic purpura ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #diagnosis #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP VS HUS ... Often hard to differentiate ... thrombocytopenic #purpura ... Comparison #Diagnosis #Table ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... disease - DIC/TTP/HUS ... - Hemolytic ... : • DIC, TTP/HUS ... #Differential #
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Production • Hemolysis ... Hepatic Uptake • Sepsis ... Post-Hepatic - Usually has ... Algorithm #Causes #Hepatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Post Transfusion Purpura ... Causes purpura & ... Occurs between 0-6 hrs ... Can lead to sepsis ... diagnosis #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... Fibrin degradation products ... hemorrhage and hemolysis ... WBC count and differential ... Diagnosis #Workup #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Post Transfusion Purpura ... Causes purpura & ... Occurs between 0-6 hrs ... Can lead to sepsis ... diagnosis #management #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of fibrin split products ... • Fibrin split products ... Skin necrosis • Purpura ... Cryoglobulinemia • TTP, HUS ... #rheumatology #hematology