13 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Imaging: CXR- pulmonary ... initiation • Differential ... #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Distributive: Sepsis ... • Obstructive: Pulmonary ... Abdominal compartment syndrome ... algorithm #treatment #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... mononeuritis multiplex WORKUP ... coagulopathy) • CBC w differential ... #differential # ... diagnosis #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
anaesthesia • Sepsis ... • Serotonin syndrome ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management ... #Workup
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... brainstem lesions, aseptic ... Behcet disease) Differential ... #diagnosis #management ... signs #symptoms #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... progression to AML ... #diagnosis #hematology
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag and APL ... toxicity → 3-10 o Sepsis ... #Hypotension #Differential ... Checklist #Diagnosis #Management ... #Workup
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... , APLA, PAC • Aseptic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis #Rheumatology
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
reservoir bag and APL ... o Aspiration, pulmonary ... Airway #Pressure #Differential ... Checklist #Diagnosis #Management ... #Workup