15 results
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm

 • Chronic Myocardial Injury: End
Myocardial Injury - Elevated ... Troponin Differential ... Diagnosis and Workup ... Shock, Hypoxemia, Anemia ... #Troponin #Differential
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Elevated LDH 5. ... Elevated beta 2 ... • Richter’s Syndrome ... Leukemia #diagnosis #workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... result in severe anemia ... immune hemolytic anemia ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... Platelet Count - Differential ... hematology for workup ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... iron deficiency anemia ... overdrive • Elevated ... Vasoplegia • Sepsis ... Acute Coronary Syndrome
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... • hemolytic anemia ... Hyperbilirubinemia • Elevated ... younger pts) Differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Erythema elevatum ... Evans • ITP • Cl-NH ... (-) hemolytic anemia ... Hematology #Monoclonal #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... if WBC > 5 or elevated ... initiation • Differential ... Differentiation #Syndrome
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Shock, Severe Anemia ... Ischemia, Compartment Syndrome ... Beta-Agonists, ↑ work ... Malaria, Late Sepsis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Eclampsia, Infection/Sepsis ... Etiology: • Pathophysiology ... Reversible course Differential ... CSF: Modestly elevated ... An elevated white