9 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Disorders - Differential ... Diagnosis and Workup ... - History of bleeding ... - Bone marrow evaluation ... #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Sequestration Disordered Platelet ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Qualitative defect in platelets ... characteristic of a platelet ... administration, evaluation ... #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... DIC • Severe Liver ... treatment #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... and decreased platelet ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... unusual bruising or bleeding ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
common following platelet ... eruptions, diarrhea, liver ... coagulopathy & ↑bleeding ... Can lead to sepsis ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... eruptions, diarrhea, liver ... coagulopathy & ↑bleeding ... Can lead to sepsis ... diagnosis #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... #diagnosis #hematology