11 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... #Diagnosis #Hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Joints (90%): Aseptic ... Demyelinating syndromes ... ) Blood (75%): Anemia
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... ) Aseptic, within ... Lupus - with Systemic
Causes of Pericarditis - Differential Diagnosis Algorithm
Viral:
 • Coxsackie
 • Echovirus
 • Adenovirus
 • Epstein-Barr virus
Diagnosis Algorithm ... arthritis • Systemic ... lupus erythematosus ... Post-cardiac injury syndrome ... #Causes #Cardiology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... Clinical Presentation ... Fever is the main clinical ... lupus erythematosus ... with leukopenia, anemia
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
neuropathy) • Systemic ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... permanent alopecia Differential ... , APLA, PAC • Aseptic ... lymphopenia, low PLT • Anemia
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... iron deficiency anemia ... Vasoplegia • Sepsis ... Acute Coronary Syndrome ... Pathophysiology #causes #cardiology
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
Diagnosis and Causes Clinical ... Hyper-eosinophilc Syndrome ... Cardiomyopathy, Systemic ... Diagnosis #Causes #differential ... #cardiology #algorithm
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... of Circulatory System ... - Compartment syndrome ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential