6 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... if WBC > 5 or elevated ... initiation • Differential ... Renal Failure ... Treatment: • Steroids
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... perfusion - shock->treatments ... before beginning treatment ... cardiac output - Acute ... peritonitis - Acute
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Immunosuppressive agents, Renal ... Reversible course Differential ... syndrome, ADEM, Acute ... CSF: Modestly elevated ... An elevated white
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... malignancy (Especially acute ... fibrinogen • Elevated ... organ damage Clinical ... Bleeding (64%) • Renal
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
important to recognize Acute ... importantly, bedside ultrasound ... Troponin may be elevated ... Cardiac cath if acute ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... sediment, and elevated ... , APLA, PAC • Aseptic ... APLA/LAC: • Renal