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diagnosis rheumatology systemic sle signs symptoms autoantibodies causes high hyperkalemia macrophage management mas mimickers pancytopenia potassium syndrome vasculitides vasculitis
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Diseases: • Systemic lupus ... erythematosus ... #Diagnosis #Hematology
Lupus Classification Spontaneous Lupus - Cutaneous Lupus Erythematosus (CLE) - Systemic Lupus Erythematosus Drug-Induced Lupus - Drug-Induced
Lupus Classification ... Erythematosus ( ... #Classification ... #rheumatology # ... diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... , APLA, PAC • Aseptic ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... (aPL) 30-45% Differential ... #Erythematosus ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Joints (90%): Aseptic ... ) Blood (75%): Anemia ... Thrombocytopenia #Lupus ... SLE #systemic #erythematosus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... erythematosus ... erythematosus [ ... with leukopenia, anemia ... Diagnosis #Management #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... ischemia - Skin: erythematous ... such as systemic lupus ... erythematosus, ... #classification
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
diseases: syßtemic lupus ... erythematosus ( ... ), sickle cell anemia ... #Hyperkalemia #Differential ... High #Potassium #Classification
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