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diagnosis rheumatology erythematosus causes sle pulmonary signs symptoms acidosis autoantibodies elevation high hyperkalemia hyperpnea hypertension lactate lactic macrophage management mas
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... #Diagnosis #Hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Joints (90%): Aseptic ... ) Blood (75%): Anemia ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... lupus erythematosus ... lupus erythematosus ... brucellosis) • Sepsis ... with leukopenia, anemia
Lupus Classification Spontaneous Lupus - Cutaneous Lupus Erythematosus (CLE) - Systemic Lupus Erythematosus Drug-Induced Lupus - Drug-Induced
Lupus Classification ... - Drug-Induced Systemic ... #Classification ... #rheumatology # ... diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... (aPL) 30-45% Differential ... Lupusreference #SLE #Systemic ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... permanent alopecia Differential ... , APLA, PAC • Aseptic ... Chronic B-cell activation
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... Chronic hemolytic anemia ... heart disease Systolic ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential
Tachypnea - Differential Diagnosis Framework Definitions • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults •
Tachypnea - Differential ... effusion/Tamponade Hematologic ... Tachypnea: • Anemia ... poisoning Nervous System ... Temperature/FEVER • Sepsis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
neuropathy) • Systemic ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... lupus erythematosus ... #diagnosis #rheumatology ... #classification
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