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diagnosis liver aflp algorithm causes obstetrics pregnancy apml bilirubinemia differentiation disease fatty hellp hepatitis icp injury jaundice obgyn oncology pathophysiology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Hepatic Uptake • Sepsis ... • Gilbert's Syndrome ... Dilatation on Ultrasound ... Algorithm #Causes #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... obstruction, HELLP Syndrome ... • Infectious: Sepsis ... Liver #Injury #Differential ... #algorithm #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Liver #Pregnancy #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
necrosis HELLP Syndrome ... and hemorrhage Acute ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #
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