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diagnosis hepatology causes acidosis acute children classification drug druginduced elevation function gastroenterology hepatitis hepatomegaly idiosyncratic lactate lactic lfts management peds
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... #Liver #Injury # ... Idiosyncratic #differential ... gastroenterology #algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Stepwise Diagnosis Algorithm ... involvement, Kidney injury ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... #Diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... #differential # ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Cholangitis • Abscess ... Hepatitis • Drug Induced ... #Causes #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... • Infectious: Sepsis ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Pyogenic liver abscess ... ) • Traumatic injury ... #abscess #pediatrics ... children #peds #differential ... #diagnosis #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... hypoperfusion - toxic-induced ... or renal injury ... assessment - assess ... Injury: • Reduced
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