13 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
Diagnosis of ascites ... albumin gradient ... syndrome, Massive liver ... #albumin #gradient ... #hepatology #differential
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... #differential # ... Diagnosis #Management ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis ... disorder (e.g. ascites ... #Injury #Diagnosis ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Diagnosis Framework ... (>1000): • DILI ... injury) • Ischemic ... #Diagnosis #hepatology
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
made in the liver ... or not by the liver ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG ... Interpretation #Differential
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... Diagnosis High ... - Massive liver ... #Differential # ... Diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... • Iatrogenic: DILI ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... • Infectious: Sepsis ... #Injury #Differential ... Acute #algorithm #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
bilirubin (Conjugated/DBili ... hepatocellular injury ... Crigler-Najjar) Albumin ... Interpretation #diagnosis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Production: • Albumin ... Unconjugated Bili ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis